2010年7月-2013年11月就职于贵州百灵企业集团制药股份有限公司；

2013年11月-至今，就职于贵州省中国科学院天然产物化学重点实验室。

代表性科研工作

(1)     Tong Zhang, Cai-Yan Tian , Ji Zhang, Qiao An, Ping Yi, Chun-Mao Yuan, Zhong-Kai Zhang, Li-Hua Zhao*, Xiao-Jiang Hao* Zhan-Xing Hu*. Quinolizidine Alkaloids and Isoflavones from the Herb of Thermopsis lupinoides and Their Antiviral, Antifungal, and Insecticidal Activities. J. Agric. Food Chem. 2024, https://doi.org/10.1021/acs.jafc.3c09529.

(2)      Ji Zhang, Tong Zhang, Qiao An, Peng Zhang, Cai-Yan Tian, Chun-Mao Yuan, Ping Yi, Zhan-Xing Hu,* Xiao-Jiang Hao*. Five quinolizidine alkaloids with anti-tobacco mosaic virus activities from two species of Sophora. Chinese Chem. Lett. 2023, https://doi.org/10.1016/j.cclet.2023.108927.

(3)  Qiao An, Ji Zhang, Peng Zhang, Lei Chen, Ping Yi, Chun-Mao Yuan, Zhan-Xing Hu,* Xiao-Jiang Hao*. Three new quinolizidine alkaloids from the roots of Sophora tonkinensis. J. Asian Nat. Prod. Res., 2023, DOI: 10.1080/10286020.2023.2221658.

(4)     Peng Zhang, Ji Zhang, Qiao An, Juan Wang, Ping Yi, Chun-Mao Yuan, Zhong-Kai Zhang, Li-hua Zhao*, Zhan-Xing Hu*, Xiaojiang Hao* Matrine-Type Alkaloids with Anti-Tomato Spotted Wilt Virus Activity from the Root of Sophora tonkinensis Gagnep. J. Agric. Food Chem. 2023, 71, 4349-4407. 

(5)  Dao-Jun Chen, Shuang Yuan, Peng Zhang, Qiao An, Ji-Bin Zou, Chun-Mao Yuan, Li-Hua Zhao*, Zhan-Xing Hu *, Xiao-Jiang Hao *. Two new isoflavones from the roots of Sophora tonkinensis. J. Asian Nat. Prod. Res., 2023, 25, 163-170.

(6)  Peng Zhang, Ji-Bin Zou, Qiao An, Ping Yi, Chun-Mao Yuan, Lie-Jun Huang, Wei Gu, Zhan-Xing Hu* & Xiao-Jiang Hao*.Two new cytisine-type alkaloids from the seeds of Thermopsis lanceolata. J. Asian Nat. Prod. Res., 2022, 24, 1141-1149.

(7)  Jing Luo, Nuoyan Wang, Ling Hua, Fei Deng, Dan Liu, Jun Zhou, Yue Yuan, Fumin Ouyang, Xuemin Chen, Shujuan Long, Yasi Huang, Zhanxing Hu*, Hong Zhou*. The Anti-Sepsis Effect of Isocorydine Screened from Guizhou Ethnic Medicine is Closely Related to Upregulation of Vitamin D Receptor Expression and Inhibition of NFκB p65 Translocation into the Nucleus. Journal of Inflammation Research, 2022:15 5649–5664.

(8)      Zhan-Xing Hu, Peng Zhang, Ji-Bin Zou, Qiao An, Ping Yi, Chun-Mao Yuan, Zhong-Kai Zhang*, Lihua Zhao*, Xiaojiang Hao* Quinolizidine Alkaloids with Antitomato Spotted Wilt Virus and Insecticidal Activities from the Seeds of Thermopsis lanceolata R. Br. J. Agric. Food Chem. 2022, 70, 9214-9226. 

(9)     Zhan-Xing Hu, Peng Zhang, Ji-Bin Zou, Qiao An, Ping Yi, Chun-Mao Yuan, Jue Yang, Wei Gu , Lie-Jun Huang, Li-hua Zhao*, Xiao-jiang Hao* Maillard Reaction Products with Anti-Tobacco Mosaic Virus Activities Generated in Processed Thermopsis lanceolata R. Br. Seed Extract J. Org. Chem. 2022, 87, 11309-11318. 

(10)  Peng Zhang, Qiao An, Ping Yi, Yue Cui, Ji-Bin Zou, Chun-Mao Yuan, Yu Zhang, Wei Gu, Lie-Jun Huang, Li-Hua Zhao*, Zhan-Xing Hu*, Xiao-Jiang Hao*. Thermlanseedlines A–G, seven thermopsine-based alkaloids with antiviral and insecticidal activities from the seeds of Thermopsis lanceolata R. Br. Fitoterapia, 2022, 158, 105140.

(11)  Zhan-Xing Hu, Ji-Bin Zou, Qiao An , Ping Yi, Chun-Mao Yuan, Wei Gu , Lie-Jun Huang, Hua-Yong Lou, Li-Hua Zhao, Xiao-Jiang Hao*. Anti-tobacco mosaic virus (TMV) activity of chemical constituents from the seeds of Sophora tonkinensis. J. Asian Nat. Prod. Res. 2021, 23, 644-651.

(12)  Jibin Zou, Lihua Zhao, Ping Yi, Qiao An, Longxiang He, Yanan Li, Huayong Lou, Chunmao Yuan, Wei Gu, Liejun Huang, Zhanxing Hu*, Xiaojiang Hao*. Quinolizidine Alkaloids with Antiviral and Insecticidal Activities from the Seeds of Sophora tonkinensis Gagnep. J. Agric. Food Chem. 2020, 68, 15015−15026. 

(13)  Zhan-Xing Hu, Qiao An, Hong-Yu Tang, Chun-Mao Yuan, Ya-Nan Li, Yu Zhang*, Xiao-Jiang Hao*. Stemtuberolines A-G, new alkaloids from Stemona tuberosa and their anti TMV activity. Fitoterapia, 2020, 143, 104572.

(14)  Zhan-Xing Hu, Qiao-An, Hong-Yu Tang, Zheng-Hong Chen, Haji Aker Aisa, Yu Zhang*, Xiao-Jiang Hao*. Acoapetaludines A-K, C20 and C19-diterpenoid alkaloids from the whole plants of Aconitum apetalum (Huth) B.Fedtsch. Phytochemistry, 2019, 167, 112111.

(15)  Zhan-Xing Hu, Li-Hua Zhao, Hong-Yu Tang, Haji Aker Aisa, Yu Zhang*, Xiao-Jiang Hao*. Seven new anthranilamide derivatives from Aconitum apetalum. Fitoterapia, 2018, 128, 73-78.

(16)  Zhan-Xing Hu, Hong-Yu Tang, Xiao-Hui Yan, Yan-Rong Zeng, Haji Aker Aisa, Yu Zhang*, Xiao-Jiang Hao*. Five new alkaloids from Aconitum apetalum (Ranunculaceae). Phytochem. Lett., 2019, 29, 6-11.

(17)  Zhan-Xing Hu, Hong-Yu Tang, Jie Guo, Haji Aker Aisa, Yu Zhang*, Xiao-Jiang Hao*. Alkaloids from the roots of Stemona tuberosa and their anti-tobacco mosaic virus activities. Tetrahedron, 2019, 75, 1711-1716.

(18)  Huirong Fan*, Zhanxing Hu, Ruixing Li, Shiqi Dongd, Yuan Gue, Ting Liu, Duanyun Si, Guangyi Liang, Changxiao Liu*. Metabolite identification of bentysrepinine (Y101), a novel anti-HBV agent in rats using a five-step strategy based on a combined workflow with two different platforms of liquid chromatography–tandem mass spectrometry. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2017, 1040: 118–128.

(19)  Zhanxing Hu, HaiJian Liao, Qiao An, Weidong Pan, Peixue Cao, Changxiao Liu, Zhengming Huang, Wen Xia, Bixue Xu*, Guangyi Liang*. Process development of clinical anti-HBV drug Y101: identification and synthesis of novel impurities. Research on Chemical Intermediates，Res. Chem. Intermedia., 2016, 42(3): 2577-2595

(20)  ZhanXing Hu, YanGong Zhang, Qiao An, BiXue Xu, WeiDong Pan, PeiXue Cao, ChangXiao Liu, ZhengMing Huang, Wen Xia, JingYing Qiu*,Guang-Yi Liang*. Development of a practical and scalable synthesis of anti-HBV drug Y101, Tetrahedron, 2014, 70 (51): 9592-9600.

(21)  Zhanxing Hu, Qiao An, Kunfeng Li, Yangong Zhang, Jingying Qiu, Bixue Xu, Weidong Pan, Peixue Cao, Changxiao Liu, Zhengming Huang, Wen Xia, and Guangyi Liang*, Identification, Synthesis, and Strategy for Minimization of Potential Impurities in the Preclinical Anti-HBV Drug Y101, Org. Process Res. Dev. 2013, 17(9), 1156−1167.

主持的主要科研项目

(1)国家自然科学基金地区基金：天然喹诺里西啶类生物碱抗番茄斑萎病毒构效关系及作用机制研究（32360105），2024.01-2027.12，32万，主持；

(2)国家自然科学基金地区基金：具有抗烟草花叶病毒活性的喹诺里西啶类生物碱的发现及其抗病机理研究（32160103），2022.01-2025.12，35万，主持；

(3)贵州省科技支撑项目：新型喹诺里西啶类绿色农药研究与示范（黔科合支撑[2021]一般181），2021.01-2023.12，32万，主持；

(4)国家自然科学基金委-贵州喀斯特中心项目子课题：山豆根的化学物质基础研究（U1812403-3-9），2019.01-2023.12，30万，主持；

(5)贵州省科技计划项目：一种新型α-葡萄糖苷酶抑制剂的设计、合成及其抗糖尿病活性研究（黔科合基础[2020]1Y398），2020.01-2022.12，10万，主持；

(6)贵州医科大学2018年度学术新苗培养及创新探索专项项目：芳香酰胺类衍生物的设计、合成、抗幽门螺旋杆菌活性及机制研究（黔科合平台人才[2018]5779－60），2018.12-2020.12，5万，主持；

以第一发明人授权的国家发明专利

(1)苦参碱类生物碱及其制备方法和应用, 胡占兴，郝小江，赵立华，安巧，易平，邹吉斌，何龙祥，专利号：ZL 2020 1 1208967.0，中国，发明专利，申请日期：2020-11-03，授权日期：2021-11-30.

(2)喹诺里西啶类生物碱及其制备方法和用途, 胡占兴，郝小江，赵立华，安巧，张鹏，邹吉斌，专利号：ZL 2022 1 0060574.2，中国，发明专利，申请日期：2022-01-09，授权日期：2023-07-04.

(3)喹诺里西啶类生物碱及其制备方法和应用, 胡占兴; 郝小江; 张鹏; 安巧; 易平; 邹吉斌; 张吉，专利号：ZL 2022 1 0448806.1，中国，发明专利，申请日期：2022-04-26，授权日期：2023-05-16.

(4)4H-3,1-苯并噁嗪-4-酮衍生物及其制备方法和应用, 胡占兴，郝小江，张鹏，陈佳林，安巧，邹吉斌，张吉，专利号：ZL 2022 1 0618159.4，中国，发明专利，申请日期：2022-06-01，授权日期：2023-08-08.

(5)一种喹诺里西啶生物碱及其制备方法和应用, 胡占兴，张鹏，郝小江，赵立华，安巧，邹吉斌，张吉，专利号：ZL 2022 1 0670329.3，中国，发明专利，申请日期：2022-06-14，授权日期：2023-11-03.